New algorithm and system for measuring size distribution of blood cells

作     者：姚翠萍 李政 张镇西 

作者机构：Key Laboratory of Biomedical Information Engineering of Ministry of Education P. R. China and Institute of Biomedical Engineering School of Life Science and Technology Xi'an Jiaotong University Xi'an 710049 Key Laboratory of Biomedical Information Engineering of Ministry of Education P. R. China and Institute of Biomedical Engineering School of Life Science and Technology Xi'an Jiaotong University Xi'an 710049n optical scattering particle sizing a numerical transform is sought so that a particle size distribution can be determined from angular measurements of near forward scattering which has been adopted in the measurement of blood cells. In this paper a new method of counting and classification of blood cell laser light scattering method from stationary suspensions is presented. The genetic algorithm combined with nonnegative least squared algorithm is employed to inverse the size distribution of blood cells. Numerical tests show that these techniques can be successfully applied to measuring size distribution of blood cell with high stability. 

出 版 物：《Chinese Optics Letters》 (中国光学快报（英文版）)

年 卷 期：2004年第2卷第6期

页      面：343-346页

核心收录：

学科分类：0808[工学-电气工程] 070207[理学-光学] 0809[工学-电子科学与技术（可授工学、理学学位）] 07[理学] 08[工学] 0805[工学-材料科学与工程（可授工学、理学学位）] 0803[工学-光学工程] 0702[理学-物理学] 

基　　金：This work was supported by the National Natural Science Foundation of China (No. 60178034) and the Natural Science Foundation of Shaanxi Province (No. 96c17) 

主　　题：Genetic algorithms Least squares approximations Light scattering Numerical methods Particle size analysis 

摘      要：In optical scattering particle sizing, a numerical transform is sought so that a particle size distribution can be determined from angular measurements of near forward scattering, which has been adopted in the measurement of blood cells. In this paper a new method of counting and classification of blood cell, laser light scattering method from stationary suspensions, is presented. The genetic algorithm combined with nonnegative least squared algorithm is employed to inverse the size distribution of blood cells. Numerical tests show that these techniques can be successfully applied to measuring size distribution of blood cell with high stability.