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Changes of Gastric Mucosal Blood Flow in the Healing Process of Peptic Ulcers

Changes of Gastric Mucosal Blood Flow in the Healing Process of Peptic Ulcers

作     者:李兆申 周岱云 许国铭 陈菊初 施雅芳 姚光弼 

作者机构:Department of GastroenterologyChanghai HospitalSecond Military Medical UniversityShanghai 200433 

出 版 物:《Journal of Medical Colleges of PLA(China)》 (中国人民解放军军医大学学报(英文版))

年 卷 期:1990年第5卷第2期

页      面:181-186,196页

学科分类:10[医学] 

主  题:gastric mucosal blood flow laser Doppler flowmetry peptic ulcers 

摘      要:Changes of gastro-duodenal mucosal blood flow (GDMBF) in the healingprocess of 82 patients with gastric ulcer,130 with duodenal ulcer and 9 with active ul-cer induced by gastric polypectomy were studied by endoscopic laser Doppler *** 108 normal subjects,the mucosal blood flow at the angle and antrum of the les-ser curvature and on the anterior wall of the duodenal bulb was the smallest (P0.01).In patients with gastric ulcer,gastric mucosal blood flow (GMBF)significantly decrea-Sed at the active stage and increased at the healing stage (P0.01 ).GDMBF significan-tly increased (P0.01) at the active stage and returned to normal at the healing stage ofduodenal *** was unchanged in the healing process of the active ulcer inducedby gastric *** mucosal blood flow at ulcer centre and margins significan-tly decreased at the active stage and markedly increased at the healing stage as compa-red with that of surrounding *** conclude that GMBF plays an importantrole in the developing and healing process of peptic ulcers.

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