Role of fractional flow reserve in guiding intervention for borderline coronary lesions

作     者：Xuekun Shi Lu Cheng 

作者机构：Affiliated Hospital of Traditional Chinese MedicineXinJiang Medical UniversityXinJiang 830000China 

出 版 物：《Family Medicine and Community Health》 (家庭医学与社区卫生（英文）)

年 卷 期：2014年第2卷第3期

页      面：18-25页

学科分类：1004[医学-公共卫生与预防医学(可授医学、理学学位)] 1002[医学-临床医学] 1001[医学-基础医学(可授医学、理学学位)] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主　　题：Coronary intervention Borderline lesion Fractional flow reserve 

摘      要：Objective:This study investigated the clinical efficacy and value of fractional flow reserve(FFR)in guiding the treatment of borderline coronary ***:Forty-three patients with borderline coronary lesions,as demonstrated by coronary angiography,and who had FFR measurements were *** patients were grouped accord-ing to FFR *** patients were evaluated 6 months after surgery to record major adverse cardiac events(MACE[sudden cardiac death,non-fatal myocardial infarction,or revasculariza-tion])and recurrence of angina ***:After the 6-month follow-up,no sudden cardiac deaths or myocardial infarctions occurred in either group,and there were no statistically significant differences(P0.05).Inter-group comparisons showed that in the groups with a FFR0.05).The recurrence rate of angina pectoris in the simple drug therapy group among the groups with a FFR0.75 was higher than the same groups with a FFR≥0.75(0.27%vs.0.05%,P0.05).Conclusion:When coronary intervention is used to treat borderline lesions,guiding inter-ventional therapy with measurement of FFR does not increase the incidence of adverse cardiovas-cular events in the short term and can better guide PCI therapy.