Characteristics of the macula in amblyopic eyes by optical coherence tomography
Characteristics of the macula in amblyopic eyes by optical coherence tomography作者机构：State Key Laboratory of Ophthalmology Zhongshan Ophthalmic Center SunYat-sen University Guangzhou 510060 Guangdong Province China Department of Ophthalmology the Fourth Affiliated Hospital Harbin Medical University Harbin 150001 Heilongjiang Province China
出 版 物：《International Journal of Ophthalmology(English edition)》 (国际眼科杂志（英文版）)
年 卷 期：2012年第5卷第2期
页 面：172-176页
核心收录：
学科分类：1002[医学-临床医学] 100212[医学-眼科学] 10[医学]
基 金：Supported by Key Projects in the Medicine Health Science and Technology from Guangzhou, China(No.201102A211005) Fundamental Research Funds of State Key Laboratory of Ophthalmology, China
主 题：amblyopia macula flava optical coherence tomography
摘 要：AIM: To test the hypothesis that amblyopic neuroretina may have an altered thickness when compared to the normal. METHODS: Twenty-five amblyopic, young patients between the ages of 7 and 11 years old were studied. The interested neuroretina areas are defined into 10 sub-regions according to superior-inferior, nasal-temoral, and pen-para axis, which cross the fovela structure. The thicknesses of ten, defined macular regions were separately measured by optical coherence tomography (OCT) and analyzed by ttest. RESULTS: The average thickness of neuroretina in the exact foveola of the amblyopic eyes is larger than that of normal eyes (P0.05), but the other nine regions have no significant difference. Interestingly, in both the normal and amblyopic eyes, the temporal area looks thinner than other quadrants (P0.05). CONCLUSION: Thickness alteration may be associated with amblyopic disorders in young patients. Studying a larger volume of subjects of similar age is required to confirm this observation.
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