Bone lesions in recurrent glucagonoma: A case report and review of literature

作     者：Cristian Ghetie Daniel Cornfeld Vassilios S Ramfidis Kostas N Syrigos Muhammad W Saif 

作者机构：Danbury Hospital Danbury CT 06810 United States Department of Diagnostic Radiology Yale School of Medicine New Haven CT 06510 United States Third Department of Medicine Sotiria General Hospital Athens Medical School Athens 11527 Greece Section of Medical Oncology Yale School of Medicine New Haven CT 06510 United States Division of Hematology and Oncology Department of Medicine Columbia University NY 10032 United States 

出 版 物：《World Journal of Gastrointestinal Oncology》 (世界胃肠肿瘤学杂志（英文版）（电子版）)

年 卷 期：2012年第4卷第6期

页      面：152-155页

核心收录：

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主　　题：Glucagonoma Bone metastases Blastic lesion Octreoscan 

摘      要：Glucagonomas are rare neuroendocrine tumors that arise from cells of the pancreatic islets. Most of them are malignant and usually present as metastatic disease. Sites most commonly involved in metastases are the liver and regional lymph nodes. Bone metastases are rare events and only a few cases have been reported in the literature. We present the case of a 53-year-old male with a medical history of recurrent non-functioning glucagonoma. He presented 17 years after the initial diagnosis with new blastic bone lesions involving the T1 vertebra and the sacrum. Diagnostic steps and medical management in metastatic glucagonoma are also reviewed.