Apoptosis in oncology

作     者：FAN XIAO QIANG, YA JUN GUO (International Joint Cancer Institute, The Second Military Medical University, Shanghai 200423, China) FAN XIAO QIANG, YA JUN GUO (International Joint Cancer Institute, The Second Military Medical University, Shanghai 200423, China)

作者机构：1International Joint Cancer Institute The Second Military Medical University Shanghai 200433 China 1International Joint Cancer Institute The Second Military Medical University Shanghai 200433 China 

出 版 物：《Cell Research》 (细胞研究(英文版))

年 卷 期：2001年第11卷第1期

页      面：1-7页

核心收录：

学科分类：0710[理学-生物学] 0831[工学-生物医学工程（可授工学、理学、医学学位）] 07[理学] 071009[理学-细胞生物学] 09[农学] 0901[农学-作物学] 090102[农学-作物遗传育种] 

主　　题：Apoptosis mitochondria death receptor death receptor ligand tumor therapy. 

摘      要：Apoptosis is a complex process involving a large array of genes and mutation of any of these genes may lead to malignancy formation. Re-acquirement of FasL by tumor cells may enable them to evade the surveillance of immune system and thus contributes to the growth of tumor. Apart from traditional therapies, inducing apoptosis of tumor cell by new methods employing death receptor ligands and making use of Fas counterattack is also being developed.