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Recent advances in plant centromere biology

Recent advances in plant centromere biology

作     者:FENG Chao LIU YaLin SU HanDong WANG HeFei BIRCHLER James HAN FangPu 

作者机构:State Key Laboratory of Plant Cell and Chromosome Engineering Institute of Genetics and Developmental Biology Chinese Academy of Sciences University of Chinese Academy of Sciences Division of Biological Sciences University of Missouri-Columbia 

出 版 物:《Science China(Life Sciences)》 (中国科学(生命科学英文版))

年 卷 期:2015年第58卷第3期

页      面:240-245页

核心收录:

学科分类:0710[理学-生物学] 0830[工学-环境科学与工程(可授工学、理学、农学学位)] 07[理学] 071007[理学-遗传学] 

主  题:着丝粒 生物学 植物 染色体分离 DNA序列 真核生物 减数分裂期 组蛋白H3 

摘      要:The centromere, which is one of the essential parts of a chromosome, controls kinetochore formation and chromosome segregation during mitosis and meiosis. While centromere function is conserved in eukaryotes, the centromeric DNA sequences evolve rapidly and have few similarities among species. The histone H3 variant CENH3(CENP-A in human), which mostly exists in centromeric nucleosomes, is a universal active centromere mark in eukaryotes and plays an essential role in centromere identity determination. The relationship between centromeric DNA sequences and centromere identity determination is one of the intriguing questions in studying centromere formation. Due to the discoveries in the past decades, including neocentromeres and centromere inactivation, it is now believed that the centromere identity is determined by epigenetic mechanisms. This review will present recent progress in plant centromere biology.

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