KINETICS OF DIFFUSION-CONTROLLED DRUG MATRICES RELEASE SYSTEM

作     者：王绍亭 杨志生 朱云仙 

出 版 物：《Chinese Journal of Chemical Engineering》 (中国化学工程学报（英文版）)

年 卷 期：1993年第1卷第1期

页      面：12-19页

核心收录：

学科分类：0817[工学-化学工程与技术] 08[工学] 

主　　题：diffusional controlled release ethylene- vinyl alcohol copolymer release kinetics 

摘      要：A refined double integral method has been applied to the problem encountered in the diffu-sion release of a drug from a polymeric *** finite external mass transfer resistance has alsobeen incorporated into the present *** release rates of 5-fluorouracil fromethylene-vinyl alcohol copolymer into distilled water were measured in order to test the applicabilityof these *** system parameters were measured by experiments and models were built *** presented here are much more accurate than Higuchi model and much easier than the *** view of accuracy,the models are almost the same as the exact *** experi-mental release data agree Well with the computed