Haemodynamic and renal effects of tadalafil in patients with cirrhosis

作     者：Georgios N Kalambokis Paraskevi Kosta Konstantinos Pappas Epameinondas V Tsianos 

作者机构：1st Division of Internal Medicine and Hepato-Gastroenterology UnitUniversity HospitalMedical School of Ioannina Department of RadiologyUniversity Hospital Department of CardiologyUniversity Hospital 

出 版 物：《World Journal of Gastroenterology》 (世界胃肠病学杂志（英文版）)

年 卷 期：2010年第16卷第39期

页      面：5009-5010页

核心收录：

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主　　题：Tadalafil Portal hypertension Cirrhosis Ascites Phosphodiesterase-5 inhibition 

摘      要：A recent report introduced the phosphodiesterase-5 inhibition by vardenafil as a novel treatment of portal hypertension in patients with *** the herein presentedletter to the editor,the administration of tadalafil did not influence portal haemodynamics but impaired systemic haemodynamics in patients with *** observations concur with the results of a report in a previous issue of World Journal of Gastroenterology(October 2008).Moreover,tadalafil adversely affected renal function in patients with decompensated liver disease.