Imaging of skeletal muscle in vitamin D deficiency

作     者：Bianca Bignotti Angela Cadoni Carlo Martinoli Alberto Tagliafico 

作者机构：Radiology DepartmentUniversity of Genoa Institute of AnatomyDepartment of Experimental MedicineUniversity of Genoa 

出 版 物：《World Journal of Radiology》 (世界放射学杂志（英文版）（电子版）)

年 卷 期：2014年第6卷第4期

页      面：119-124页

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

基　　金：Supported by Partially founded by the European Society of Musculoskeletal Radiology,Young Investigator Grant to Alberto Tagliafico UNIGE,No.PRA 2012 

主　　题：Muscle Vitamin D Vitamin D deficiency Ultrasound Computed tomography Magnetic resonance imaging 

摘      要：Elderly people are prone to accidental falls and one of the main risk factor is considered muscle weakness. Several studies focused on muscle weakness and muscle morphology changes in the elderly that may be associated with vitamin D deficiency. The prevalence of vitamin D deficiency is higher than previously though representing an important issue for public health and prevention. There is an increased interest in vitamin D effects in skeletal muscle and imaging modalities are particularly involved in this field. In patients with vitamin D deficiency, ultrasound, computed tomography, densitometry and magnetic resonance imaging(MRI) can efficiently describe changes in muscle morphology and size. Moreover, new imaging modalities, such as MRI spectroscopy, may improve knowledge about the metabolic effects of vitamin D in skeletal muscle. In this narrative review we will discuss the role of skeletal muscle imaging in vitamin D-deficient individuals. The aim of this paper is to improve and encourage the role of radiologists in this field.