A New Method of Crystallization of Octahydro Trisodium Salt of Fructose- 1,6-diphosphate

作     者：应汉杰 欧阳平凯 

作者机构：DepartmentofPharmacySchoolofPharmaceuticalandLifeScienceNanjingUniversityofChemicalTechnologyNanjing210009China 

出 版 物：《Chinese Journal of Chemical Engineering》 (中国化学工程学报（英文版）)

年 卷 期：2002年第10卷第2期

页      面：208-211页

核心收录：

学科分类：0710[理学-生物学] 0830[工学-环境科学与工程（可授工学、理学、农学学位）] 081704[工学-应用化学] 0817[工学-化学工程与技术] 08[工学] 081701[工学-化学工程] 0703[理学-化学] 

基　　金：Supported by the National Eighth Five-Year Key Project of China 

主　　题：octahydro trisodium salt of fructose-1 6-diphosphate ethanol-sodiumacetate system crystallization 

摘      要：In order to overcome the elementary heterogeneous nucleation whileoctahydro trisodium salt of fructose- 1, 6-diphosphate (FDPNa_3·8H_2O) is crystallized with ethanol precipitation at low temperature,a new crystallization method with alcohol precipitation combined withsalt precipitation has been presented. The ethanol-sodium ac- etatesystem for crystallization of salt of fructose-1, 6-diphosphate isbased on the mechanism of crystallization of FDPNA_3·8H_2O in theethanol-low temperature system. It is found that crystal size may becontrolled by regulating Temperature of pH value of solution in thecrystallization process, and the crystal yield increases to 95/100from 78/100 Which obtained in the ethanol-low temperature system.