Adenosine Sensitivity is Associated with Ablation Success Rate and Recurrence Rate with Nonirrigated Catheters in Patients with Ventricular Premature Contractions/Tachycardia from the Ventricular Outflow Tract

作     者：Xiang-FeiFeng Qun-Shan Wang Jian Sun Rui Zhang Peng-Pai Zhang Jun Wang Da-Li Feng Yi-Gang Li Feng Xiang-Fei;Wang Qun-Shan;Sun Jian;Zhang Rui;Zhang Peng-Pai;Wang Jun;Feng Da-Li;Li Yi-Gang

作者机构：Department of Cardiology Xinhua Hospital Shanghai Jiao Tong University School of Medicine Shanghai 200092 China Metropolitan Heart and Vascular Institute Minneapolis MN. USA 

出 版 物：《Chinese Medical Journal》 (中华医学杂志（英文版）)

年 卷 期：2015年第128卷第2期

页      面：147-152页

核心收录：

学科分类：0710[理学-生物学] 090603[农学-临床兽医学] 1002[医学-临床医学] 07[理学] 09[农学] 0906[农学-兽医学] 071003[理学-生理学] 

主　　题：Ablation Adenosine Catheter Ventricular Tachycardia Premature Ventricular Contractions 

摘      要：Background：A high ablation success rate for ventricular arrhythmia （VA） from outflow tract has been achieved,but some of them cannot be eliminated from *** investigated the association between adenosine sensitivity and ablation success/recurrence rates with a nonirrigated or an irrigated ***：According to adenosine test,all patients were divided into a sensitive group （S group） or an insensitive group （Ⅰ group）.The patients of each group were randomized into a nonirrigated catheter （NA） subgroup or an irrigated catheter （IA） subgroup with a 2∶1 ***：In S group of 122 patients （84 in NA subgroup）,the ablation success rate was similar between two subgroups （94.7% vs.90.5%,P 〉 0.05）,but in Ⅰ group of 94 patients （60 in NA subgroup）,it was higher in IA subgroup （94.1%） than that in NA subgroup （73.3%,P 〈 0.05）.The success rate using nonirrigated catheter was significantly higher in S group （90.5%） than that in Ⅰ group （73.3%,P 〈 0.01）,and the recurrence rate was lower in S group than that in Ⅰ group （1.3%,vs.13.6%,P 〈 0.05）.On the contrary,the success rate and the recurrence rate using irrigated catheter were similar between S group and 1 group （94.7%,94.1%,P 〉 0.05,vs.2.8%,6.3%,P 〉 0.05）.Conclusions：Adenosine insensitivity is associated with a lower success rate and a higher recurrence rate for VA patients undergoing nonirrigated catheter ***,irrigated catheters should be the first choice for VA ablation in adenosine insensitive patients.