Phyllofenone A, a New Scalarane Sesterterpene from the Sponge Phyllospongia Foliascens(Pallas)

作     者：John K. Snyder 

作者机构：Department of Chemistry Boston University Boston USAhe present paper covers the structure of a new sesterterpene phyllofenone A(1) isolated from the South China Sea sponge Phyllospongia foliascens. Phyllofenone A is a member of the scalarane class of sesterterpenes with a (C-20 C-24)-bishomo-(C-25)-nortetra-cyclic skeleton. The structure charcterization was based on one- and two-dimensional NMR and mass spectroscopy with the assistance of molecular modeling. Phyllofenone A shows weak antifungal activity against Candida pseudotropicalis. 

出 版 物：《Chemical Research in Chinese Universities》 (高等学校化学研究（英文版）)

年 卷 期：1991年第7卷第2期

页      面：100-106页

核心收录：

学科分类：07[理学] 0703[理学-化学] 

基　　金：Supported by the National Natural Science Foundation of China 

主　　题：Sponge Sesterterpene Selective INEPT 2D NMR 

摘      要：The present paper covers the structure of a new sesterterpene, phyllofenone A(1) , isolated from the South China Sea sponge Phyllospongia foliascens. Phyllofenone A is a member of the scalarane class of sesterterpenes with a (C-20, C-24)-bishomo-(C-25)-nortetra-cyclic skeleton. The structure charcterization was based on one- and two-dimensional NMR and mass spectroscopy with the assistance of molecular modeling. Phyllofenone A shows weak antifungal activity against Candida pseudotropicalis.