Outcomes after liver transplantation for combined alcohol and hepatitis C virus infection

作     者：Rashid Khan Ashwani K Singal Bhupinderjit S Anand 

作者机构：Division of Gastroenterology and HepatologyUniversity of Texas Medical BranchGalvestonTX 77555United States Division of Gastroenterology and HepatologyUniversity of Alabama BirminghamBirminghamAL 35294-0012United States Department of Gastroenterology and HepatologyMichael DeBakey VA CenterBaylor College of MedicineHoustonTX 77030United States 

出 版 物：《World Journal of Gastroenterology》 (世界胃肠病学杂志（英文版）)

年 卷 期：2014年第20卷第34期

页      面：11935-11938页

核心收录：

学科分类：1002[医学-临床医学] 100210[医学-外科学(含：普外、骨外、泌尿外、胸心外、神外、整形、烧伤、野战外)] 10[医学] 

主　　题：Alcoholic liver disease Hepatitis C virus Liver transplantation Graft survival Mortality 

摘      要：Alcohol abuse and chronic hepatitis C virus(HCV)infection are two major causes of chronic liver disease in the United *** 10%-15%of liver transplants performed in the United States are for patients with cirrhosis due to combined alcohol and HCV *** on outcomes on graft and patient survival,HCV recurrence,and relapse of alcohol use comparing transplants in hepatitis C positive drinkers compared to alcohol abuse or hepatitis C alone are conflicting in the *** studies report a slightly better overall outcome in patients who were transplanted for alcoholic cirrhosis vs those transplanted for HCV alone or for combined HCV and alcohol related ***,some other studies do not support these ***,most studies are limited to a retrospective design or small sample *** prospective multicenter studies are needed to better define the outcomes in hepatitis C drinkers.