Visible light promoted synthesis of N-aroylsulfoximines by oxidative C–H acylation of NH-sulfoximines

作     者：Wenlong Jiang Youming Huang Lihong Zhou Qingle Zeng 

作者机构：State Key Laboratory of Geohazard Prevention and Geoenvironment Protection College of Materials Chemistry & Chemical Engineering Chengdu University of Technology Chengdu 610059 China College of Environment and Ecology Chengdu University of Technology Chengdu 610059 China 

出 版 物：《Science China Chemistry》 (中国科学（化学英文版）)

年 卷 期：2019年第62卷第9期

页      面：1213-1220页

核心收录：

学科分类：07[理学] 0703[理学-化学] 

基　　金：supported by the National Natural Science Foundation of China(21372034) the State Key Laboratory of Geohazard Prevention and Geoenvironment Protection(SKLGP2018Z002) 

主　　题：visible light aldehyde sulfoximines acylation oxidative dehydrogenative coupling 

摘      要：The visible light-promoted synthesis of N-aroylsulfoximines has been accomplished via an oxidative dehydrogenative coupling at room temperature under air without the addition of a photosensitizer, metal catalyst, or base. This process exhibits good functional group tolerance, allows facile isolation and purification, and affords N-aroylsulfoximines with high efficiency. The efficiency of the newly developed protocol is described in detail with 27 examples with yields ranging from 80% to 96%.Furthermore, the chirality of the NH-sulfoximine is completely maintained in the desired N-aroylsulfoximine product(99% ee).