Long-term outcome of correction of tetralogy of Fallot in 56 adult patients

作     者：ZHENG Da-wei SHAO Guo-feng FENG Qiang NI Yi-ming 

作者机构：Department of Cardiothoracic Surgery the First Affiliated HospitalZhejiang University School of Medicine Hangzhou Zhejiang310003 China Department of Cardiothoracic Surgery Ningbo Medical CentreLihuili Hospital Ningbo Zhejiang 315041 China 

出 版 物：《Chinese Medical Journal》 (中华医学杂志（英文版）)

年 卷 期：2013年第126卷第19期

页      面：3675-3679页

核心收录：

学科分类：1002[医学-临床医学] 100210[医学-外科学(含：普外、骨外、泌尿外、胸心外、神外、整形、烧伤、野战外)] 10[医学] 

基　　金：This study was supported by a grant from the Natural Science Foundation ofNingbo  Zhejiang (No. 2011A610036) 

主　　题：tetralogy of Fallot pulmonary regurgitation pulmonary artery pressure congenital heart disease 

摘      要：Background Although most patients with tetralogy of Fallot undergo radical repair during infancy and childhood,patients that remain undiagnosed and untreated until adulthood can still be *** study aimed to evaluate longterm outcomes of adult patients with tetralogy of Fallot who were treated surgically,and to determine the predictors of postoperative pulmonary *** Fifty-six adult patients underwent complete surgical ***-three patients （76.8%） required a transannular ***,diastolic,and mean pressure in the main pulmonary artery were measured after *** The early mortality rate was 3.6%.The 16-year survival rate was （84.4±11.5）%.Late echocardiography revealed 41 patients with transannular patch who had pulmonary regurgitation,consisting of mild pulmonary regurgitation in 28 patients,moderate in eight,and severe regurgitation in five *** addition,there was right ventricular outflow tract stenosis in nine patients,moderate/severe tricuspid valve regurgitation in seven,and residual ventricular septal defect in *** regression analysis demonstrated that the mean pulmonary pressure measured just after repair predicted late pulmonary *** The long-term survival of surgically treated adult patients with tetralogy of Fallot is *** mean pressure 〉20 mmHg in the main pulmonary artery measured right after surgical repair may be a feasible reference to time the reconstruction of the pulmonary valve.