Role of formyl peptide receptor 2(FPR2) in the normal brain and in neurological conditions

作     者：Wei-Yi Ong John Jia En Chua 

作者机构：Department of Anatomy Yong Loo Lin School of Medicine National University of Singapore Singapore Life Sciences Institute Neurobiology Research Programme National University of Singapore Singapore Department of Physiology National University of SingaporeSingaporeInstitute of Molecular and Cell Biology Agency for Science Technology and Research (A*STAR) Singapore 

出 版 物：《Neural Regeneration Research》 (中国神经再生研究（英文版）)

年 卷 期：2019年第14卷第12期

页      面：2071-2072页

核心收录：

学科分类：0710[理学-生物学] 1002[医学-临床医学] 1001[医学-基础医学(可授医学、理学学位)] 10[医学] 

主　　题：Role receptor normal brain 

摘      要：There is much recent interest in the role of the anti-inflammatory molecules and their receptors in the normal brain and in neurological disorders. The formyl peptide receptor (FPR) subfamily of G protein-coupled receptors play important roles in these processes. Binding to specific peptides triggers activation of FPRs, leading to signalling events that regulate inflammatory responses. One member of this subfamily of receptors is FPR2, also known as ALX (the lipoxin A4 (LXA4) receptor). FPR2 is specifically activated by LXA4 and resolvin D1 (RvD1)(Pirault and B.ck, 2018).