Rectal carcmosarcoma: A case report and review of literature

作     者：Dimitrios Konstantinos Tsekouras Stylianos Katsaragakis Dimitrios Theodorou Georgia Kafiri Fotis Archontovasilis Panagiotis Giannopoulos Panagiotis Drimousis John Bramis 

作者机构：University De partment of General Surgery Athens School of MedicineIppokration HospitalAthensGreece Department of Pathology Ippokration HospitalAthensGreece 

出 版 物：《World Journal of Gastroenterology》 (世界胃肠病学杂志（英文版）)

年 卷 期：2006年第12卷第9期

页      面：1481-1484页

核心收录：

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主　　题：Carcinosarcoma Rectum 

摘      要：A 60-years old male was admitted to our department for investigation of constipation and hypogastric discomfort intensified during defecation of a few weeks duration. The cause proved to be a rectal carcinosarcoma that was treated by abdominoperineal resection and postoperative chemo-radiotherapy. The patient died 6 months later due to hepatic failure, showing evidence of disseminated disease. In general colonic carcinosarcomas constitute a rare category of malignant neoplasms whose nature is still incompletely understood. No specific treatment guidelines exist. Surgery is the mainstay of treatment and regardless of the addition of adjuvant therapy the prognosis is very poor. Systematic genetic analysis may be the clue for understanding the pathogenesis of these mysterious tumors.