Rhodium(Ⅲ)-catalyzed intermolecular cyclization of anilines with sulfoxonium ylides toward indoles

作     者：Zhihao Shen Chao Pi Xiuling Cui Yangjie Wu 

作者机构：Department of Chemistry Henan Key Laboratory of Chemical Biology and Organic Chemistry Key Laboratory of Applied Chemistry of Henan UniversitiesZhengzhou University 

出 版 物：《Chinese Chemical Letters》 (中国化学快报（英文版）)

年 卷 期：2019年第30卷第7期

页      面：1374-1378页

核心收录：

学科分类：07[理学] 0703[理学-化学] 

基　　金：partial financial support from the Ministry of Science and Technology of China (No. 2016YFE0132600) Zhengzhou University 

主　　题：Rhodium Cyclization Aniline Sulfoxonium ylide Indole 

摘      要：Rhodium(Ⅲ)-catalyzed synthesis of indole derivatives has been realized via cascade reaction of C -H alkylation/nucleophilic cyclization starting from readily available N-phenylpyridin-2-amines and sulfoxonium ylides. Notably, this transformation could smoothly proceed with high yields, good regioselectivity, and feature broad group tolerance and under redox-neutral condition to avoid external oxidant. The titled products are potentially important building blocks in the organic synthesis through various chemical transformations.