Effect of Glutamine Supplementation on Intestinal Mucosal Protein,DNA and Mucosal Morphology of Early-Weaned Piglets

作     者：ZHANG Jun-min and GAO Zhen-chuan(Institute of Animal Science , Chinese Academy of Agricultural Sciences , Beijing 100094 . P. R. China) 

作者机构：Institute of Animal Science Chinese Academy of Agricultural Sciences Beijing 100094 P.R.China 

出 版 物：《Agricultural Sciences in China》 (中国农业科学（英文版）)

年 卷 期：2002年第1卷第12期

页      面：1376-1381页

学科分类：0905[农学-畜牧学] 09[农学] 

主　　题：Glutamine Early-weaned piglet Intestinal mncosal morphology 

摘      要：Forty piglets weaned at 21 days age were randomly assigned to one of two groups. The treatment group contained 1. 2% glutamine. The diets were calculated to be isonitrogenous and isoenergetic, each treatment contained five replicates of four piglets. Five piglets from each dietary treatment were killed at 35 days and 49 days age. The results showed that dietary glutamine supplementation increased jejunal DNA content of piglets in the treatment group at 35 days and 49 days age. There was no significant change of ileum DNA content and intestinal protein content between the treatment and control ones. Dietary glutamine supplementation increased mucosal thickness of piglets in treatment group markedly at 35 days age. The intestinal villus heights were significantly higher in treatment than that in control. The results of electron micrograph showed that dietary glutamine supplementation prevented deterioration of intestinal epithelium, and maintained normal intestinal microvillus structure. The results suggested that glutamine supplementation prevented villus atrophy, and had protective effect on intestinal structure.