Roles of the Hedgehog Signaling Pathway in Cutaneous Physiology and Oncology
Roles of the Hedgehog Signaling Pathway in Cutaneous Physiology and Oncology作者机构：Department of PathologyHospital for Skin Diseases(Institute of Dermatology)Chinese Academy of Medical Sciences and Peking Union Medical CollegeNanjingJiangsu 210042China
出 版 物：《International Journal of Dermatology and Venereology》 (国际皮肤性病学杂志（英文）)
年 卷 期：2019年第2卷第2期
页 面：77-83页
学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
基 金：supported by PUMC Youth Fund(No.3332017168)
主 题：Hedgehog Signaling Oncology pathogenesis
摘 要：IntroductionThe role of the hedgehog signaling pathway (HSP),which is involved in both physiological and pathological processes,has gained interests in the field of dermatology.1 Recently,increasing evidence has revealed the role of the HSP in several cutaneous tumors as well as in some hematological *** activation of the HSP contributes to malignant processes in these tumors,such as pathogenesis,malignant invasion,metastasis,drug-resistance,cancer-ization,and cancer stem cell *** the HSP may serve as a crucial component of tumorigenesis,we discuss the influences exerted by the HSP in cutaneous physiology and oncology in this article.
维普期刊数据库
同方期刊数据库