Rethinking to riluzole mechanism of action: the molecular link among protein kinase CK1δ activity, TDP-43 phosphorylation, and amyotrophic lateral sclerosis pharmacological treatment
Rethinking to riluzole mechanism of action: the molecular link among protein kinase CK1δ activity, TDP-43 phosphorylation, and amyotrophic lateral sclerosis pharmacological treatment作者机构：Molecular Modeling Section (MMS) Department of Pharmaceutical and Pharmacological Sciences University of Padova
出 版 物：《Neural Regeneration Research》 (中国神经再生研究（英文版）)
年 卷 期：2019年第14卷第12期
页 面：2083-2085页
核心收录：
学科分类：10[医学]
主 题：riluzole mechanism Life future
摘 要：Life expectancy in industrialized and developed countries will continue to increase in the near future. Consequently, over the last years, the incidence and social impact of neurodegenerative diseases have increased, highlighting an urgent need for new and more effective therapeutic strategies to counter these terrible disorders. While we tend to think about neurodegenerative diseases as conditions that are uniquely associated with the elder age, these diseases cover a diverse range across the entire lifespan, even affecting infants and children.
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