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Thirty Years of Multiple Sequence Codes

Thirty Years of Multiple Sequence Codes

作     者:Edward N. Trifonov 

作者机构:Genome Diversity Center Institute of Evolution University of Haifa Haifa 31905 Israel Division of Functional Genomics and Proteomics Faculty of Science Masaryk University Brno 61137 Czech Republic 

出 版 物:《Genomics, Proteomics & Bioinformatics》 (基因组蛋白质组与生物信息学报(英文版))

年 卷 期:2011年第9卷第1期

页      面:1-6页

核心收录:

学科分类:0710[理学-生物学] 1001[医学-基础医学(可授医学、理学学位)] 07[理学] 071007[理学-遗传学] 0714[理学-统计学(可授理学、经济学学位)] 0703[理学-化学] 0701[理学-数学] 0812[工学-计算机科学与技术(可授工学、理学学位)] 

基  金:supported by Grant 222/09 of Israel Science Foundation  and by Fellowship of SoMoPro (South Moravian Program  Czech Republic) with financial contribution of European Union within the seventh framework program (FP/2007-2013  Grant No. 229603) 

主  题:genomic code chromatin code second genetic code code interaction code degeneracy 

摘      要:An overview is presented on the status of studies on multiple codes in genetic sequences. Indirectly, the existence of multiple codes is recognized in the form of several rediscoveries of Second Genetic Code that is different each time. A due credit is given to earlier seminal work related to the codes often neglected in literature. The latest developments in the field of chromatin code are discussed, as well as perspectives of single-base resolution studies of nucleosome positioning, including rotational setting of DNA on the surface of the histone octamers.

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