Relationship between Occurrence and Progression of Lung Cancer and Nocturnal Intermittent Hypoxia, Apnea and Daytime Sleepiness

作     者：Wei LIU Miao LUO Yuan-yuan FANG Shuang WEI Ling ZHOU Kui LIU 

作者机构：Department of Respiratory and Critical Care Medicinethe Central Hospital of WuhanTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430014China Department of Respiratory and Critical Care MedicineTongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China Departments of Medical Oncologythe Third Affiliated Hospital of Kunming Medical University (Tumor Hospital of Yunnan Province)Kunming 65011& China 

出 版 物：《Current Medical Science》 (当代医学科学（英文）)

年 卷 期：2019年第39卷第4期

页      面：568-575页

核心收录：

学科分类：10[医学] 

基　　金：This project was supported by the National Natural Science Foundation of China (No.81300064) 

主　　题：lung cancer nocturnal intermittent hypoxia apnea daytime sleepiness obstructive sleep apnea syndrome 

摘      要：The possible relationship between lung cancer and nocturnal intermittent hypoxia,apnea and daytime sleepiness,especially the possible relationship between the occurrence and progression of lung cancer and obstructive sleep apnea syndrome (OSAS) was ***-five cases of primary lung cancer suitable for surgical resection at the Third Affiliated Hospital of Kunming Medical University between January 2017 and December 2017 were recruited (lung cancer group),and there were 45 patients in the control group who had no significant differences in age,sex and other general data from lung cancer *** analyzed covariates included general situation,snore score,the Epworth Sleeping Scale (ESS),Pittsburgh Sleep Quality Index (PSQI),apnea and hypopneas index (AHI),oxygen desaturation index 4 (ODk),lowest arterial oxygen saturation [LSpCh (%)],oxygen below 90% of the time [T90%(min)],the percentage of the total recorded time spend below 90% oxygen saturation (TS90%),to explore the possible relationship between lung cancer and above *** participants were followed up for one *** results showed that:(1) There was significant difference in body mass index (BMI),ESS,AHI,T90%(min),TS90%,ODh,snore score and LSpCh (%) between lung cancer group and control group (P0.05);(2) Patients in the lung cancer group were divided into OSAS subgroup and non- OSAS subgroup according to the international standard for the diagnosis of *** was significant difference in BMI,age,staging,incidence of concurrent hypertension and concurrent CHD,snore score,ESS score,T90%(min),TS90%,ODh and LSpCh (%) between OSAS subgroup and non-OSAS subgroup (P0.05).There was no statistically significant difference in gender,PSQI score,incidence of concurrent diabetes,smoking history an