Systematical study of the mechanistic factors regulating genome dynamics in vivo by CRISPRsie
作者机构：National Institute of Biological SciencesBeijing 102206China Peking University-Tsinghua University-National Institute of Biological Sciences Joint Graduate ProgramSchool of Life SciencesPeking UniversityBeijing 100871China Graduate School of Peking Union Medical CollegeBeijing 100730China Tsinghua Institute of Multidisciplinary Biomedical ResearchTsinghua UniversityBeijing 100084China
出 版 物：《Journal of Molecular Cell Biology》 (分子细胞生物学报（英文版）)
年 卷 期：2019年第11卷第11期
页 面：1018-1020页
核心收录：
学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
基 金：the National Natural Science Foundation of China(81572795 and 81773304) the‘Hundred,Thousand and Ten Thousand Talent Project’by Beijing Municipal Government(2017A02) the National Natural Science Foundation of China(31701135).We thank Beijing Municipal Government and the Ministry of Science and Technology of China for funds allocated to NIBS.D.H.and Y.Z.conceived the study.D.H.,X.M.t G.L.J.D.,Y.H.y Q.H.f J.X.f and X.S.performed experiments and analyzed data.Y.Z.analyzed data and wrote the manuscript with support from all authors
主 题：dynamics vivo regulating
摘 要：The spatiotemporal regulation of threedimensional(3D)genome dynamics has been implicated in various genome functions including gene transcription,DNA recombination,DNA replication,and DNA repair(Bickmore,2013).
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