Arnie Levine and the MDM2-p53 discovery:a postdoctoral fellow's perspective

作     者：Gerard P.Zambetti Gerard P.Zambetti

作者机构：Department of PathologySt. Jude Children's Research Hospital262 Danny Thomas PlaceMemphisTN 38105USA 

出 版 物：《Journal of Molecular Cell Biology》 (分子细胞生物学报（英文版）)

年 卷 期：2019年第11卷第7期

页      面：620-623页

核心收录：

学科分类：0710[理学-生物学] 07[理学] 09[农学] 

基　　金：National Institutes of Health, NIH American Cancer Society, ACS Damon Runyon Cancer Research Foundation, DRCRF 

主　　题：dinner group time 

摘      要：It was early 1990 that we had gathered at Arnie Levine s home for dinner to celebrate the transition of several postdoctoral fellows to faculty positions in *** a new postdoctoral fellow in his lab,I was thrilled to have the opportunity to spend some personal time with *** were discussing the paradigm shift made by his group a year earlier that p53 is a tumour suppressor (Finlay et at.,1989) and not an on cogene,as origi nally thought for a decade after its original discovery (Lane and Crawford,1979;Linzer and Levine,1979).