Small-molecule targeting of oncogenic FTO demethylase in acute myeloid leukemia

出 版 物：《Science Foundation in China》 (中国科学基金（英文版）)

年 卷 期：2019年第27卷第2期

页      面：45-45页

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主　　题：FTO Small-molecule targeting of oncogenic FTO demethylase in acute myeloid leukemia AML 

摘      要：With the support of the National Natural Science Foundation of China and the Chinese Academy of Sciences,the laboratory led by Yang CaiGuang(杨财广)from Shanghai Institute of Materia Medica,Chinese Academy of Sciences,has identified a potential therapeutic small molecule for treating the acute myeloid leukemia(AML)by targeting the oncogenic RNA demethylase FTO,which was published in Figure Schematic diagram of small-molecular targeting of the oncogenic FTO *** Cell(2019,35:677—691).