Long-term efficacy of excimer laser in situ keratomileusis in the management of children with high anisometropic amblyopia

作     者：LIN Xiao-ming YAN Xiao-he WANG Zheng YANG Bin CHEN Qi-wen SU Jin-ai YE Xue-lian 

作者机构：State Key Laboratory of Ophthalmology Zhongshan OphthalmicCenter Sun Yat-sen University Guangzhou Guangdong 510060China 

出 版 物：《Chinese Medical Journal》 (中华医学杂志（英文版）)

年 卷 期：2009年第122卷第7期

页      面：813-817页

核心收录：

学科分类：1002[医学-临床医学] 100212[医学-眼科学] 10[医学] 

基　　金：Research Foundation of Science and Technology Plan Project  Guangdong  China [A052001016  200713031505002] 

主　　题：excimer laser in situ keratomileusis amblyopia children anisometropia 

摘      要：Background Children with anisometropic amblyopia are often noncompliant with traditional treatment including spectacules and contact lenses. This study was to evaluate the long-term efficacy of excimer laser in situ keratomileusis （LASIK） for children with high anisometropic amblyopia. Methods A retrospective analysis of 24 children with high unilateral anisometropic amblyopia, who underwent LASIK during the period between August 2000 and September 2005 in our hospital, was conducted. The mean age of these children was （7.4±1.9） years （range 5-14 years） and the mean follow-up period was （33.3±14.2） months （range 18.5-74.2 months）. After LASIK, visual acuity, refraction and far or near stereoacuity were analyzed. Near stereoacuity was measured by the random-dot butterfly stereogram and the pre-school random-dot stereogram, while far stereoacuity was measured by the synoptophore with Yan＇s random-dot stereogram. Results Mean preoperative uncorrected visual acuity was 0.06±0.05, while mean postoperative uncorrected visual acuity was elevated to 0.43±0.33. Mean preoperative best-corrected visual acuity was 0.26±0.22, while mean postoperative best-corrected visual acuity was elevated to 0.67±0.40. For patients with myopic anisometropia, preoperative mean spherical equivalent refraction was （-8.01±2.70） D while postoperative value significantly reduced to （-1.32±2.47） D. For patients with hyperopic anisometropia, preoperative mean spherical equivalent refraction was （ 7.35±1.55） D while postoperative value significantly reduced to （3.30±0.86） D. These results demonstrated that there was statistical difference in these parameters between preoperative and postoperative tests. At the last follow-up, 20 patients had near stereoacuity, and the mean near stereoacuities measured by the random-dot butterfly stereogram and the preschool random-dot stereogram were （149.00±152.93）＂ and （201.05±235.94）＂, respectively. In contrast, 11 patients had far stereoacuity, and the mean far