The mechanisms of traditional Chinese medicine underlying the prevention and treatment of atherosclerosis

作     者：LI Ting-Ting WANG Zhi-Bin LI Yang CAO Feng YANG Bing-You KUANG Hai-Xue 

作者机构：Key Laboratory of Chinese Materia Medica (Ministry of Education) Heilongjiang University of Chinese Medicine 

出 版 物：《Chinese Journal of Natural Medicines》 (中国天然药物（英文版）)

年 卷 期：2019年第17卷第6期

页      面：401-412页

核心收录：

学科分类：100506[医学-中医内科学] 1006[医学-中西医结合] 1005[医学-中医学] 100602[医学-中西医结合临床] 10[医学] 

基　　金：supported by the Excellent Innovative Talent Support Program of Heilongjiang University of Chinese Medicine(No.2012RCD05) 

主　　题：Atherosclerosis Traditional Chinese medicine Mechanism 

摘      要：Atherosclerosis(AS) is a chronic inflammatory disease associated with high morbidity and mortality. The incidence of AS is increasing in the last decades. So development of safe and effective therapeutics for treating AS has become prominently important. Although there are numerous chemical drugs available for treating AS, some drugs are not effective and some have serious side effects. Traditional Chinese medicine(TCM) has a long history for the prevention and treatment of AS due to its less side effects and superior efficacy. This paper describes the effectiveness and underlying mechanisms for prevention and treatment of AS by TCM or its active components. Some TCM, e.g. XuemaiNing, Tongxinluo and Salvia miltiorrhiza have been reported to have cardio-protective effect. Some active components of TCM, e.g. saikosaponin-A, kuwanon G, luteolin and β-elemene have been isolated from various TCM and demonstrated to have beneficial effects on prevention and treatment of AS.