Pathological factors affecting gastric adenocarcinoma survival in a Caribbean population from 2000-2010
Pathological factors affecting gastric adenocarcinoma survival in a Caribbean population from 2000-2010作者机构：The Department of Surgery Radiology Anaesthesia and Intensive Care The University of the West IndiesJamaica 999172 West Indies College of Public Health University of South Florida Tampa FL 33620-9951 United States The Department of Pathol-ogy The University of the West Indies Jamaica 999172 West Indies Tropical Medicine Research Institute The Univer-sity of the West Indies Jamaica 999172 West Indies
出 版 物：《World Journal of Gastrointestinal Surgery》 (世界胃肠外科杂志（英文版）（电子版）)
年 卷 期：2014年第6卷第6期
页 面：94-100页
学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
主 题：Gastric adenocarcinoma Caribbean Jamaica Pathologic Survival Gastrectomy Gastritis Helicobacter pylori Cardia Circumferential resection margin
摘 要：AIM: To investigate pathological factors related to long term patient survival post surgical management of gas-tric adenocarcinoma in a Caribbean ***: This is a retrospective, observational study of all patients treated surgically for gastric adenocarci-noma from January 1st 2000 to December 31 st 2010 at The University Hospital of the West Indies, an urban Jamaican hospital. Pathological reports of all gastrecto-my specimens post gastric cancer resection during the specified interval were accessed. Patients with a final diagnosis other than adenocarcinoma, as well as pa-tients having undergone surgery at an external institu-tion were excluded. The clinical records of the selected cohort were reviewed. The following variables were analysed; patient gender, patient age, the number of gastrectomies previous performed by the lead surgeon, the gross anatomical location and appearance of the tumour, the histological appearance of the tumour, infil-tration of the tumour into stomach wall and surround-ing structures, presence of Helicobacter pylori and the presence of gastritis. Patient status as dead vs alive was documented for the end of the interval. The effect of the aforementioned factors on patient survival were analysed using Logrank tests, Cox regression models, Ranksum tests, Kruskal-Wallis tests and Kaplan-Meier ***: A total of 79 patients, 36 males and 43 fe-males, were included. Their median age was 67 years(range 36-86 years). Median survival time from surgery was 70 mo with 40.5% of patients dying before the termination date of the study. Tumours ranged from 0.8 cm in size to encompassing the entire stomach speci-men, with a median tumour size of 6 cm. The median number of nodes removed at surgery was 8 with a maximum of 28. The median number of positive lymph nodes found was 2, with a range of 0 to 22. Patients median survival time was approximately 70 mo, with 40.5% of the patients in this cohort dying before the terminal date. An
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