Clinical Observation on Treatment of Diabetic Nephropathy by Tangweikang(糖微康)Capsule

作     者：LIN Lan NI Qing GAO Qi-jian ZHANG Run-yun HU Dong-peng LIU Xi-ming SU Cheng-lian CHEN Si-lan WEI Jun-ping LI Ming-di 林兰;倪青;高齐健;张润云;胡东鹏;刘喜明;苏诚炼;陈思兰;魏军平;李鸣镝

作者机构：Guang''anmen HospitalChina Academy of TCMBeijing(100053) 

出 版 物：《Chinese Journal of Integrative Medicine》 (中国结合医学杂志(英文版))

年 卷 期：2002年第8卷第1期

页      面：19-23页

学科分类：1006[医学-中西医结合] 1005[医学-中医学] 10[医学] 

基　　金：The study belonged to State"Nine Five"Key Projects(No.9690607) 

主　　题：Tangweikang capsule diabetic nephropathy renal function 

摘      要：Objective:To observe the effect of Tangweikang Capsule(糖微康,TWK)on diabetic nephropathy(DN).Methods:The 119 DN patients were divided into two groups:the group of TWK treatment(n=78)and group of captopril(n=41)as the control,the dose of which was 50 mg/*** treatment lasted for 12 *** changes of symptom score,urinary microprotein series,blood glucose,renal function,*** ***:The total effective rate of the TWK group was 84.62%;and that of the control group was 70.73%,there was significant difference between the two groups(P0.05).TWK treatment reduced the levels of blood glucose,blood lipid,serum creatinine,blood urea nitrogen,albumin,β2 microglobulin and Tamm Horsfall protein(P0.05,P0.01)in DN *** levels of triglyceride,angiotensinⅠ,angiotensinⅡ,atrial natriuretic polypeptide,prostaglandins,endothelin,typeⅣcollagen and total cholesterol decreased and the level of high density lipoprotein cholesterol increased in the serum of TWK treated DN patients(P0.05,P0.01).Conclusion:TWK exerted obviously ameliorating effect on renal function in DN patients.