Incidence of congenital heart diseases in Chinese children with non-syndromic congenital blepharoptosis:a prospective observational study of 1053 patients

作     者：Le-Feng Zeng Zheng-De Tang Jun Gu Chang-Qian Wang Hui-Li Zhang Le-Feng Zeng;Zheng-De Tang;Jun Gu;hang-Qian Wang;Hui-Li Zhang

作者机构：Department of CardiologyShanghai Ninth People’s HospitalShanghai Jiaotong University School of Medicine639 Zhizaoju RoadShanghai200011China 

出 版 物：《World Journal of Pediatrics》 (世界儿科杂志（英文版）)

年 卷 期：2020年第16卷第4期

页      面：411-415页

核心收录：

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

基　　金：This work was supported by the National Natural Science Foundation of China grant(Grant no.81570037) the MDT Program of Shanghai Ninth People’s Hospital(Grant no.2017-1-015) 

主　　题：Congenital blepharoptosis Congenital heart diseases Echocardiography 

摘      要：Background Congenital blepharoptosis(CBP)may be part of a large spectrum of birth defects presenting with other ocular or systemic ***,the aim of the study was to investigate the incidence of congenital heart diseases(CHD)in CBP children not associated with specific *** A total of 1053 Chinese children diagnosed with non-syndromic CBP were consecutively enrolled and their cardiac structure was evaluated by *** Forty children were identified with ***-four children had one type of structural malformation(simple CHD).Sixteen children had two or more types of structural malformation(complex CHD).CHD and complex CHD were more prevalent in patients with severe or bilateral *** analysis revealed that presence of severe ptosis and bilateral ptosis was independently associated with CHD *** We found an increased frequency of CHD in CBP children,suggesting a clinical need for routine echocardiography evaluation in CBP,especially in children with severe or bilateral ptosis.