MDR:an integrative DNA N6-methyladenine and N4-methylcytosine modification database for Rosaceae
作者机构：Hainan Key Laboratory for Biology of Tropical Ornamental Plant GermplasmInstitute of Tropical Agriculture and ForestryHainan University570228 HaikouChina State Key Laboratory of OphthalmologyZhongshan Ophthalmic CenterSun Yat-sen University510060 GuangzhouChina Inner Mongolia Academy of Agricultural and Animal Husbandry Sciences010031 HuhhotChina Department of AgronomyCollege of AgriculturePurdue UniversityWest LafayetteIN 47907USA
出 版 物：《Horticulture Research》 (园艺研究（英文）)
年 卷 期：2019年第6卷第1期
页 面：774-780页
核心收录：
学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
基 金：supported by grants from the National Natural Science Foundation of China(grant numbers 31760316,31600667,and 31871326) Priming Scientific Research Foundation of Hainan University(grant number KYQD(ZR)1721) Science Foundation for The Youth Teachers of Hainan University in 2017(grant number hdkyxj201702)
主 题：database adenine modification
摘 要：Eukaryotic DNA methylation has been receiving increasing attention for its crucial epigenetic regulatory *** recently developed single-molecule real-time(SMRT)sequencing technology provides an efficient way to detect DNA N6-methyladenine(6mA)and N4-methylcytosine(4mC)modifications at a single-nucleotide *** family Rosaceae contains horticultural plants with a wide range of economic ***,little is currently known regarding the genome-wide distribution patterns and functions of 6mA and 4mC modifications in the *** this study,we present an integrated DNA 6mA and 4mC modification database for the Rosaceae(MDR,http://***).MDR,the first repository for displaying and storing DNA 6mA and 4mC methylomes from SMRT sequencing data sets for Rosaceae,includes meta and statistical information,methylation densities,Gene Ontology enrichment analyses,and genome search and browse for methylated sites in *** provides important information regarding DNA 6mA and 4mC methylation and may help users better understand epigenetic modifications in the family Rosaceae.
维普期刊数据库