Iron(Ⅲ) phthalocyanine chloride-catalyzed oxidation–aromatization of α,β-unsaturated ketones with hydrazine hydrate: Synthesis of 3,5-disubstituted 1H-pyrazoles

作     者：赵军龙 邱骏 苟小锋 花成文 陈邦 Junlong Zhao;Jun Qiu;Xiaofeng Gou;Chengwen Hua;Bang Chen

作者机构：西北大学化学与材料科学学院，合成与天然功能分子化学教育部重点实验室陕西西安710069 

出 版 物：《Chinese Journal of Catalysis》 (催化学报（英文）)

年 卷 期：2016年第37卷第4期

页      面：571-578页

核心收录：

学科分类：081704[工学-应用化学] 07[理学] 0817[工学-化学工程与技术] 08[工学] 070303[理学-有机化学] 0703[理学-化学] 

基　　金：supported by the Industrial Research Project of Shaanxi Science and Technology Department(2014K08-29) Science and Technology Plan Project of Xi’an(CXY1511(7)) Scientific Research Foundation of Northwest University~~ 

主　　题：Iron(III) phthalocyanine chloride Aromatization Pyrazole Michael addition Recyclable catalyst Green chemistry 

摘      要：We have developed an iron（III） phthalocyanine chloride‐catalyzed oxidation–aromatization ofα,β‐unsaturated ketones with hydrazine hydrate. Various 3,5‐disubstituted 1H‐pyrazoles were obtained in good to excellent yields. This method offers several advantages, including room‐tem‐perature conditions, short reaction time, high yields, simple work‐up procedure, and use of air as an oxidant. The catalyst can be recovered and reused five times without loss of activity.