Vitamin D Status in Primary Hypothyroid Subjects Attending a Specialized Endocrine Center of Bangladesh
Vitamin D Status in Primary Hypothyroid Subjects Attending a Specialized Endocrine Center of Bangladesh作者机构：Department of Endocrinology Mainamoti Medical College Comilla Bangladesh Department of Endocrinology Mymensingh Medical College Hospital Mymensingh Bangladesh Department of Endocrinology Dhaka Medical College Dhaka Bangladesh
出 版 物：《Open Journal of Endocrine and Metabolic Diseases》 (内分泌与新陈代谢疾病期刊（英文）)
年 卷 期：2019年第9卷第5期
页 面：61-68页
学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学]
主 题：Primary Hypothyroidism Vitamin D
摘 要：Background: Association between vitamin D deficiency and hypothyroidism has been reported by many authors though the study results are mixed. Objective: The study was conducted to observe vitamin D status among primary hypothyroid subjects. Materials/Methods: In this single-center cross-sectional study, 356 subjects with primary hypothyroidism (either new or previously diagnosed) were evaluated for serum thyroid stimulating hormone (TSH) and 25(OH) vitamin D levels. 25(OH)D levels were classified as normal (≥30 ng/ml), insufficient (20 to 29.9 ng/ml), and deficient (≤20 ng/ml). Results: The mean age of the study subjects was 36.33 (±12.44) years;majority of them were female (89.9%), homemaker (79.8%), residing in urban or suburban areas (64%), and literate (85.7%);almost half (48%) of them were obese. Their median TSH was 6.17 μIU/ml and mean 25(OH)D was 25.16 (±12.18) ng/ml. The frequencies of vitamin D deficiency and insufficiency were 39.6% and 34.3% respectively. No statistical differences were observed in 25(OH)D levels between males and females, obese and non-obese, new cases and previously diagnosed cases, new cases with subclinical and overt hypothyroidism, the previously diagnosed cases with controlled and uncontrolled hypothyroidism, and among subjects living in urban, suburban and rural areas. Serum 25(OH) vitamin D level showed no correlations with age, body mass index (BMI) and TSH levels of the study subjects. Conclusion: The observed frequency of hypovitaminosis D (deficiency and insufficiency) was high (73.9%) in primary hypothyroid subjects from Bangladesh.
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