Animal models for studying penile hemodynamics

作     者：Hiroya Mizusawa Osamu Ishizuka Osamu Nishizawa HIROYA MIZUSAWA~;OSAMU ISHIZUKA~;OSAMU NISHIZAWA~ ~DEPARTMENT OF UROLOGY;NATIONAL NAGANO HOSPITAL;--;MIDORIGAOKA;UEDA;JAPAN ~DEPARTMENT OF UROLOGY;SHINSHU UNIVERSITY SCHOOL OF MEDICINE;--;ASAHI;MATSUMOTO;JAPAN

作者机构：Department of Urology National Nagano Hospital 1-27-21 Midorigaoka Ueda 386 0022 JapanDepartment of Urology Shinshu University School of Medicine 3-1-1 Asahi Matsumoto 390 8621 JapanDepartment of Urology Shinshu University School of Medicine 3-1-1 Asahi Matsumoto 390 8621 Japan 

出 版 物：《Asian Journal of Andrology》 (亚洲男性学杂志（英文版）)

年 卷 期：2002年第4卷第3期

页      面：225-228页

核心收录：

学科分类：10[医学] 

主　　题：erectile dysfunction impotence intracavernous pressure sexual dysfunction corpus cavernosum electrophysiology 

摘      要：Animal models for the study of erectile function monitoring the changes in intracavernous pressure (ICP) during penile erection was reviewed. The development of new models using small commercially-available experimental animals, rats and mice, in the last decade facilitated in vivo investigation of erectile physiology. The techniqueenabled to evaluate even subtle erectile responses by analyzing ICP and systemic blood pressure. Moreover, the method has been well improved and studies using conscious animal models without the influence of any drug or anesthesia are more appropriate in exploring the precise physiological and pharmacological mechanisms in erection. Also, more natural and physiological sexual arousal instead of electrical or pharmacological stimulation is desirable in most of the *** article reviewed the development of ICP studies in rats and mice.