Synthesis and Crystal Structure of N-Hydroxy-9-(3’,4’-methylene- dioxyphenyl)-1,8-dioxo-1,2,3,4,5,6,7,8,9, 10-decahydroacridine in Aqueous Media

作     者：史达清 牟杰 庄启亚 王香善 

作者机构：Department of Chemistry Xuzhou Normal University Xuzhou 221116 ChinaKey Laboratory of Biotechnology on Medical Plants of Jiangsu Province Xuzhou 221116 China Department of Chemistry Xuzhou Normal University Xuzhou 221116 China 

出 版 物：《Chinese Journal of Structural Chemistry》 (结构化学（英文）)

年 卷 期：2005年第24卷第9期

页      面：1073-1077页

核心收录：

学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学] 

基　　金：This work was supported by the Foundation of "Innovation Project" of Xuzhou Normal University 

主　　题：crystal structure N-hydroxylacridine green chemistry 

摘      要：The title compound N-hydroxy-9-（3＇,4＇-methylenedioxyphenyl）-1,8-dioxo-1,2,3,4,5,6,7,8,9,10-decahydroacridine （C2oH19NO5, Mr=353.36） is of orthorhombic, space group Pna2t with a=14.6914（16）, b=8.8103（10）, c=12.6648（14）A°, Z=4, V=1639.3（3） A°^3 Dc=1.432 g/cm^3, μ（MoKa）=0.103 mm^-1, F（000）=744, R=0.0445 and wR=0.1043 for 2172 observed reflections （I〉 2σ（I））. X-ray analysis reveals that the pyridine and cyclohexane rings adopt boat and half-chair configurations, respectively. In addition, there is an intermolecular hydrogen bond （O（1）-H…O（3）） in the title molecule.