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The role of Eph receptors in lens function and disease

The role of Eph receptors in lens function and disease

作     者:SON Alexander I. PARK Jeong Eun 

作者机构:Department of Chemical BiologyErnest Mario School of PharmacyRutgersThe State University of New Jersey 

出 版 物:《Science China(Life Sciences)》 (中国科学(生命科学英文版))

年 卷 期:2012年第55卷第5期

页      面:434-443页

核心收录:

学科分类:1002[医学-临床医学] 100212[医学-眼科学] 10[医学] 

基  金:NEI NIH HHS [R01 EY019012] Funding Source: Medline 

主  题:cataract lens EphA2 ephrin-A5 

摘      要:Cataract is the single largest contributor to blindness in the world,with the disease having a strong genetic *** recent years the Eph family of receptor tyrosine kinases has been identified as a key regulator in lens *** this review we discuss the roles of the Eph receptors in lens biology and cataract development.

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