Purification,initial characterization and immune activities of polysaccharides from the fungus,Polyporus umbellatus

作     者：Ye Sun Xiaoyan Zhou 

作者机构：Department of BiologyShanghai Institute of TechnologyShanghai 201418PR China Shanghai Institute of Industrial MicrobiologyShanghai 200233PR China 

出 版 物：《Food Science and Human Wellness》 (食品科学与人类健康（英文）)

年 卷 期：2014年第3卷第2期

页      面：73-78页

学科分类：0832[工学-食品科学与工程（可授工学、农学学位）] 1004[医学-公共卫生与预防医学(可授医学、理学学位)] 08[工学] 083202[工学-粮食、油脂及植物蛋白工程] 

基　　金：Shanghai Institute of Technology Science and Technology Development Foundation(No.KJ2002-15) 

主　　题：polysaccharides fungus weights 

摘      要：Polyporus umbellatus(formerly Grifola umbellatus),an edible fungus,has been used as traditional Chinese *** present investigation aimed to uncover the active ingredients in this fungal species,with the emphasis on its *** polysaccharides,one from fermented mycelium and the other from the fruiting body,were chromatographically *** weights,anti-microbial and immune activities of the polysaccharides were *** mycelium polysaccharide was found to have a molecular weight of 857 kDa and consist of glucose and galactose at a molar ratio of 1.57:1,while the one from the fruiting body,679 kDa in molecular weight,was also made up of glucose and galactose but at a molar ratio of 5.42:*** immune assays,these fungal polysaccharides increased the killing potency of natural killer(NK)and lymphokineactivated killer(LAK)cells from mouse spleen and promoted proliferation of mouse B and T ***,both *** mycelium and its extract were found to inhibit Escherichia coli and Staphylococcus aureus,but had no effects on Aspergillus niger or Aspergillus *** results indicated that fermented *** mycelium is indeed immune active,most probably due to its ingredients of *** consumption of this fungus may be beneficial for human health.