Protection Efficacy of Recombinant Infectious Laryngotracheitis Vaccine in Chicks
Protection Efficacy of Recombinant Infectious Laryngotracheitis Vaccine in Chicks作者机构：Faculty of Veterinary Science Mahidol University Salaya Phuttamonthon Nakhon Pathom 73170 Thailand CEVA Animal Health （Thailand） Ltd Bangkok 10400 Thailand
出 版 物：《Journal of Agricultural Science and Technology(A)》 (农业科学与技术（A）)
年 卷 期：2011年第1卷第8期
页 面：1112-1114页
学科分类：090603[农学-临床兽医学] 09[农学] 0906[农学-兽医学]
主 题：Recombinant vaccine infectious laryngotracheitis fowl pox vectored seroconversion eye lesion score
摘 要：A commercial recombinant fowl pox vectored infectious laryngotracheitis （ILT） vaccine was examined its protection efficacy in one-day-old chicks by subcutaneous route with various dose-strength. The treatment groups I-III birds were vaccinated with a full, 1/2 and 1/3 dose of recommendation dose, respectively. Thereafter, at 6 wk post vaccination, they were challenged with 5x labeled dose of live ILT vaccine. Protection efficacy of the vaccine was compared among groups based on antibody production and eye lesion score. The results of eye lesion score showed that there was a significant difference between control and treatment groups, whereas the difference was not found among the treatment groups. For seroconversion, there was no significant difference between birds in group I and II. However, higher number of seroconversion birds in groups I and II than group III was observed （P 〈 0.05）. It was concluded that a half dose of recommendation dose had the same protection efficacy as a full dose of recombinant YP-LT vaccine.
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