The role of gut micorbiome in obesity and diabetes
作者机构：Department of Pediatric Gastroenterology and HepatologyClinical Hospital No 1ul.3-go Maja 13-1541-800 ZabrzePoland Department of PediatricsInstitute of MedicineUniversity of Opole45-418 OpolePoland
出 版 物：《World Journal of Pediatrics》 (世界儿科杂志（英文版）)
年 卷 期：2019年第15卷第4期
页 面：332-340页
核心收录：
学科分类：1004[医学-公共卫生与预防医学(可授医学、理学学位)] 1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学]
主 题：Diabetes Microbiome Obesity
摘 要：Background Obesity and diabetes became a grooving problem in both adults and *** hypotheses concerned agents involved in the excessive weight gain process and it s *** only genetic or environmental factors,but also intestinal microbiome seems to play a role in the pathophysiology of this *** sources A systematic review was conducted using Pubmed as the medical database *** concerning connection between microbiome and metabolic disorders such as obesity and diabetes from last 10 years were *** Intestinal bacteria may be involved both in the development of obesity,and its further *** pro-inflammatory and immunomodulating effect of dysbiosis are possible triggers of insulin resistance and *** interventions aimed at the microbiome,as well as attempts to modify the microbiome at later stages may become new opportunities in the prevention and treatment of obesity and carbohydrate metabolism *** The gut microbiome has been shown to be an important part of the metabolic *** use of probiotic,prebiotics and symbiotics is promising,but requires further investigations to determine the specific metabolic effects of each bacteria strain and substance.
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