Latency represents sound frequency in mouse IC

作     者：QIU Qiang TANG Jie YU ZuLin ZHANG Juan ZHOU YingJie XIAO ZhongJu SHEN JunXian 

作者机构：State Key Laboratory of Brain and Cognitive SciencesInstitute of BiophysicsChinese Academy of SciencesBeijing 100101China Graduate University of Chinese Academy of SciencesBeijing 100049China Department of PhysiologySouthern Medicine UniversityGuangzhou 510515China 

出 版 物：《Science China(Life Sciences)》 (中国科学（生命科学英文版）)

年 卷 期：2007年第50卷第2期

页      面：258-264页

学科分类：0710[理学-生物学] 07[理学] 071003[理学-生理学] 

基　　金：the National Natural Science Foundation of China(Grant Nos.30170250,90208012,and 30270440) the Innovation Program of the Chinese Academy of Sciences(Grant No.KGCX2-SW-602-2) Natural Science Founda-tion of Guangdong Province(Grant No.32870) 

主　　题：first spike latency characteristic frequency representation inferior colliculus mouse 

摘      要：Frequency is one of the fundamental parameters of *** frequency of an acoustic stimulus can be represented by a neural response such as spike rate,and/or first spike latency(FSL)of a given *** spike rates/frequency function of most neurons changes with different acoustic ampli-tudes,whereas FSL/frequency function is highly *** implies that FSL might represent the fre-quency of a sound stimulus more efficiently than spike *** study involved representations of acoustic frequency by spike rate and FSL of central inferior colliculus(IC)neurons responding to free-field pure-tone *** found that the FSLs of neurons responding to characteristic frequency(CF)of sound stimulus were usually the shortest,regardless of sound intensity,and that spike rates of most neurons showed a variety of function according to sound frequency,especially at high *** results strongly suggest that FSL of auditory IC neurons can represent sound frequency more precisely than spike rate.