Quantitative analysis using ELISA of vascular endothelial growth factor and basic fibroblast growth factor in human colorectal cancer,liver metastasis of colorectal cancer and hepatocellular carcinoma

作     者：Muriel Mathonnet Bernard Descottes Denis Valleix Francois Labrousse Véronique Truffinet Yves Denizot 

作者机构：Service de Chirurgie DigestiveEndocrinienne et GénéraleCHU Dupuytren2 avenue Luther KingLimoges 87045France Service de Chirurgie Viscérale et TransplantationCHU Dupuytren2 avenue Luther King87045 LimogesFrance Service d'Anatomo-PathologieCHU Dupuytren2 avenue Luther King87045 LimogesFrance UMR CNRS 6101Faculté de Médecine2 rue Docteur Marcland87025 LimogesFrance 

出 版 物：《World Journal of Gastroenterology》 (世界胃肠病学杂志（英文版）)

年 卷 期：2006年第12卷第23期

页      面：3782-3783页

核心收录：

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

基　　金：Supported by La Ligue Nationale Francaise Contre le Cancer (Comitéde la Corrèze et de la Haute Vienne) 

主　　题：Vascular endothelial growth factor Basicfibroblast growth factor Colorectal cancer Hepatocellularcarcinomas 

摘      要：Angiogenesis consists of the sprouting of capillaries from pre-existing vessels. It is well-known that tumor growth is angiogenesis-dependent. Vascular endothelial growth factor （VEGF） and basic fibroblast growth factor （bFGF） stimulated vascular endothelial cell proliferation and are involved in the neoplastic angiogenesis of several types of tumors including those of the intestinal tract. Authors usually investigated VEGF and using immunohistochemistry bFGF protein expressions or Western blotting and VEGF and bFGF transcripts using reverse transcriptase Dolymerase chain reaction （RT-PCR）.