Prescription pattern of anti-malarial drugs in a tertiary care hospital

作     者：Santoshkumar R Jeevangi Manjunath S Sharanabasappa M Awanti 

作者机构：Dept of PharmacologyM.R.Medical CollegeGulbarga-585105Karnataka StateIndia Dept of BiochemistryM.R.Medical CollegeGulbarga-585105Karnataka StateIndia 

出 版 物：《Asian Pacific Journal of Tropical Medicine》 (亚太热带医药杂志（英文版）)

年 卷 期：2010年第3卷第5期

页      面：379-381页

核心收录：

学科分类：1007[医学-药学(可授医学、理学学位)] 1002[医学-临床医学] 10[医学] 

主　　题：Malaria Chloroquine Artesunate Drug utilization Drug use indicators 

摘      要：Objective:To evaluate the prescribing pattern of anti malarial drugs in a tertiary care hospital. Methods:A prospective cross-sectional study was conducted for 6 months of patients visiting in Basaveshwar Teaching and General Hospital,*** were analyzed for various drug use ***:A total of 212 prescriptions were collected,with 136(64.15%) male and 76(35.85%) *** were 128(60.37%) Plasmodium vivax cases and 84(39.63%) Plasmodium falciparum *** Plasmodium vivax cases were treated with chloroquine alone and among these 16(12.5%) recieved radical treatment with primaquine along with *** 84 patients with Pasmodium falciparum,40 patients received single drug such as quinine/ mefloquinine/artesunate/*** 44 patients received multidrug regime like,quinine+artesunate(54.54%),quinine+mefloquine(27.27%) and quinine+arteether (18.18%).Chloroquine was not administered to any of the patients with Plasmodium falciparum *** most common adverse effects with chloroquine were anorexia,nausea,vomiting and tinnitus in 9.37% of the *** quinine it was nausea and vomiting in 17.64% ,tinnitus in 11.76% and hypoglycemia in 2.1% of ***:Our study found the perennial favorites like chloroquine for Plasmodium vivax and quinine for Plasmodium falciparum were the most effective *** the severe Plasmodium falciparum cases the artesunate derivatives and combination of artesunate with quinine/mefloquine were most effective with fewer incidences of side effects.