胃食管反流病患者食管体部运动障碍:这一现象真的与反流相关吗?

作     者：Ciriza De Los Ros C Garca Menéndez L Dez HernándezA 程欣 

作者机构：C/Emiliano Barral 13B4 A 28043 Madrid Spain Dr 

出 版 物：《世界核心医学期刊文摘（胃肠病学分册）》 (Core Journals in Gastroenterology)

年 卷 期：2005年第1卷第8期

页      面：50-51页

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主　　题：胃食管反流 运动障碍 食管括约肌 管体 运动异常 压力过低 活动异常 静态压力 压力正常 收缩功能 

摘      要：Background: Esophageal motility abnormalities have been observed in patients w ith gastroesophageal reflux disease. Goals:The aim of the present study was to d etermine if esophageal motor disorders in patients with a positive response to t he omeprazole test are related to the existence of reflux or they are concomitan t findings. Study: A 24-hour pH monitoring and a stationary manometry were perf ormed on 128 patients: 49 of them had normal manometry, 31 hypotensive lower eso phageal sphincter, 29 motor disorder in esophageal body, and 19 hypotensive lowe r esophageal sphincter and motor disorder in esophageal body. Results: We found an association between the presence of abnormal reflux and motor disorder in eso phageal body (χ2 test; P 0.05). However, ineffective esophageal motility was t he disorder most strongly related to reflux, where as the hypercontractile disor ders were not clearly attrib- uted to it. Conclusions: Esophageal manometric abnor- malities should be considered cautiously before considering a motor disorder a s a consequence of abnormal reflux.