Celiac disease and microscopic colitis:A report of 4 cases

作     者：Zsolt Barta Eva Zold Arpad Nagy Margit Zeher Istvan Csipo 

作者机构：3rd Department of MedicineInstitute for Internal MedicineMedical and Health Science CenterUniversity of Debrecen 

出 版 物：《World Journal of Gastroenterology》 (世界胃肠病学杂志（英文版）)

年 卷 期：2011年第17卷第16期

页      面：2150-2154页

核心收录：

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主　　题：Collagen colitis Lymphocytic colitis Celiac disease Fibrosing alveolitis Anti-saccharomyces cerevisiae antibody 

摘      要：Celiac disease (CD) is an autoimmune disorder of the small intestine that occurs in genetically predisposed people at all ***,it can be associated also to other immunopathological disorders,and may be associated with abnormal histology in segments of the gut other than the small bowel including colonic *** guidelines for endoscopic investigation of the jejunum are well defined,no indication is defined for colonic *** describe four cases of concurrent CD and microscopic colitis (MC) diagnosed at our department over a 10-year period and analyzed the main features and outcomes of CD in this *** symptoms of these patients were improved initially by a gluten-free diet before the onset of MC *** of the patients were siblings and had an atypical form of *** other two patients with CD and MC also presented with fibrosing alveolitis and were anti-Saccharomyces cerevisiae antibody *** co-existence of immune-mediated small bowel and colonic inflammatory and pulmonary diseases are not well-known,and no systematic approach has been used to identify the lifelong patterns of these immune-based *** can develop,or present with CD at any stage in life,which can co-exist with other gastrointestinal diseases of (auto-) immune *** addition,the fa-milial co-existence and prevalence of MC in patients with a prior diagnosis of CD are *** managing celiac disease should be aware of these associations and understand when to consider colon investigation.