Pafuranones A and B, two dimeric polyketides from a rare marine algae-derived fungus Paraconiothyrium sp.

作     者：Yuqi Du Zhengbo Chen Hao Li Yi Wang Peng Fu Weiming Zhu 

作者机构：Key Laboratory of Marine DrugsMinistry of Education of ChinaSchool of Medicine and PharmacyOcean University of ChinaQingdao 266003China Laboratory for Marine Drugs and Bioproducts of Pilot National Laboratory for Marine Science and TechnologyQingdao 266003China 

出 版 物：《Chinese Chemical Letters》 (中国化学快报（英文版）)

年 卷 期：2019年第30卷第5期

页      面：981-984页

核心收录：

学科分类：07[理学] 0703[理学-化学] 

基　　金：financially supported by the National Natural Science Foundation of China(Nos.41876172,41806086,U150122141376148&U1606403) the Fundamental Research Funds for the Central Universities(No.201841006) 

主　　题：Pafuranone Dimer Fungus Paraconiothyrium sp. Enteromorpha prolifera 

摘      要：Pafuranones A(1)and B(2),a pair of new epimeric polyketide dimers,were isolated from the fungus Paraconiothyrium ***-3316 associated with the marine algae Enteromorpha *** structures,including absolute configurations,were fully elucidated based on spectroscopic analysis,calculated ECD,and chemical *** A(1)and B(2)possess a rare dimeric furanone skeleton,which might be formed through a conjugate addition of the monomeric units followed by an intramolecular cyclization.