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Insecticide susceptibility status and resistance mechanism of Anopheles cracens Sallum and Peyton and Anopheles maculatus Theobald(Family: Culicidae) from knowlesi malaria endemic areas in Peninsular Malaysia

Insecticide susceptibility status and resistance mechanism of Anopheles cracens Sallum and Peyton and Anopheles maculatus Theobald(Family: Culicidae) from knowlesi malaria endemic areas in Peninsular Malaysia

作     者:Ahmad Rohani Abdul Rahman Aidil Azahary Ke-Xin Yu Mohamed Nor Zurainee Wan Mohamad Ali Wan Najdah Han Lim Lee 

作者机构:Medical Entomology Unit Institute for Medical Research(Malaysia) Department of Parasitology University of Malaya Faculty of Health and Life Sciences Management and Science University(Malaysia) 

出 版 物:《Asian Pacific Journal of Tropical Medicine》 (亚太热带医药杂志(英文版))

年 卷 期:2019年第12卷第2期

页      面:79-86页

核心收录:

学科分类:1001[医学-基础医学(可授医学、理学学位)] 100103[医学-病原生物学] 10[医学] 

主  题:Insecticide susceptibility Vector control WHO adult bioassay Biochemical enzyme assay 

摘      要:Objective: To assess the insecticide susceptibility status of Anopheles cracens(***) and Anopheles maculatus(***) from knowlesi malaria endemic areas in Peninsular Malaysia towards DDT, malathion and deltamethrin and to determine the resistance mechanism ***: Adult and larval mosquitos were collected for *** status of Anopheles was determined using the standard WHO adult bioassay, larval bioassay and biochemical enzyme ***: WHO adult bioassay results indicated *** collected from Kampung Sungai Ular, Pahang was resistant towards 4% DDT, while *** collected from Kampung Sokor, Kelantan and Kampung Sungai Lui, Selangor exhibited resistance towards 4% ***, the enzyme activity profiles varied according to strains and *** resistance ratio of larval bioassay, showed that all strains and species tested were susceptible to malathion and ***: Since only a few anopheline strains exhibited low level of insecticide resistance towards malathion, DDT and *** insecticides are still considered effective for vector control program towards *** and ***.

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