Comparison of peripapillary and macular choroidal thickness and ganglion cell complex thickness in glaucomatous and healthy eyes

作     者：Yuli Park Hong Kyu Kim Kyong Jin Cho 

作者机构：Department of Ophthalmology Dankook University Hospital Dankook University College of Medicine 

出 版 物：《International Journal of Ophthalmology(English edition)》 (国际眼科杂志（英文版）)

年 卷 期：2019年第12卷第4期

页      面：603-606页

核心收录：

学科分类：10[医学] 

基　　金：the ICT R&D program of MSIT/IITP(No.2018-0-00242 Development of AI ophthalmologic diagnosis and smart treatment platform based on big data) 

主　　题：choroidal thickness ganglion cell complex optical coherence tomography glaucoma 

摘      要：AIM: To assess choroidal thickness(CT) and its association with ganglion cell-inner plexiform layer thickness(GCIPLT) and retinal nerve fiber layer thickness(RNFLT) in open angle glaucoma(OAG) comparing with preperimetric glaucoma(PPG) and normal ***: Totally 55 eyes of OAG, 40 eyes of PPG, and 40 eyes of age-matched normal eyes were studied. Peripapillary CT(PCT), macular CT(MCT), RNFLT, and GCIPLT were evaluated. Relationship between the CT with RNFLT and GCIPLT were studied. The correlation between CT and confounding variables as gender, age, intraocular pressure, and visual field mean deviation were analyzed. RESULTS: Mean PCT were 113.6±39.1 μm in OAG, 116.3±42.7 μm in PPG, and 148.9±41.7 μm in normal eyes. PCT and MCT was thinner in OAG compared to healthy eyes. There was a significant correlation for PCT and mean RNFLT in 1, 2, 6, and 7 clock hours of OAG eyes. The difference in PCT remained after adjusting for axial length, age, and disc area(P=0.003). No significant correlation was shown between MCT and mean GCIPLT in all ***: PCT is thinner in OAG and PPG compared with healthy eyes. The correlation of RNFLT and PCT found in OAG and PPG is not revealed in normal eyes.