Metabolism of pectenotoxins in brown crabs Cancer pagurus fed with blue mussels Mytilus edulis

作     者：李兆新 

作者机构：Yellow Sea Fishery Research Institute Norwegian School of Veterinary Science 

出 版 物：《Chinese Journal of Oceanology and Limnology》 (中国海洋湖沼学报（英文版）)

年 卷 期：2009年第27卷第3期

页      面：468-472页

核心收录：

学科分类：0710[理学-生物学] 0908[农学-水产] 0707[理学-海洋科学] 0906[农学-兽医学] 09[农学] 0815[工学-水利工程] 

基　　金：Supported by Norwegian International Education Funding Quota Program 

主　　题：pectenotoxin metabolism LC-MS/MS Cancerpagurus Mytilus edulis 

摘      要：We investigated the metabolism of pectenotoxins in brown crabs(Cancer pagurus).The crabs were fed with blue mussels(Mytilus edulis) for 21 d then depurated for 42 *** extracted the toxins from the digestive glands of contaminated crabs,uncontaminated crabs(control group),and the meat of blue mussels using *** of the crab digestive glands were fractionated by liquid-liquid partitioning and solid phase *** fractions were analyzed by liquid chromatography coupled with tandem mass spectrometry(LC-MS/MS) and liquid chromatography coupled with ion-trap mass spectrometry(LC-MSn).We detected a new PTX-like compound,designated as *** MS2 mass spectrum of the metabolite-1 [M+Na]+ ion at m/z 897.5 revealed fragment ions at m/z 853.5 and 555.5,typical of those exhibited by other pectenotoxins.